The Hope Cancer Support Centre was founded on Easter week 1999. It all began when a small number of people met in Enniscorthy and went for a cup of coffee in a local hotel. They decided they would meet each Friday morning for a chat and support each other on their cancer journey. Other people from the area, who were also living with cancer, soon heard of this group and wanted to join them. Within a very short period, the number had grown significantly and it became obvious there was a need to establish a more permanent structure to those meetings.

The use of a building in Church Street Enniscorthy was acquired and this became their regular meeting place. With a rapid growing membership it became clear there was a huge need for a cancer support centre in the area to provide support and information to people throughout County Wexford and beyond.